Enhancing Lung Cancer Prediction Accuracy UsingQuantum-Enhanced K-Medoids with Manhattan Distance
DOI:
https://doi.org/10.30812/matrik.v24i3.4190Keywords:
Clustering, data mining, K-Medoids, Manhattan Distance, Quantum Bit, Quantum ComputingAbstract
Lung cancer is a leading cause of cancer-related deaths worldwide, and early detection plays a crucial
role in improving treatment outcomes. This study proposes an enhancement of the K-Medoids clustering
method by integrating a quantum computing approach using Manhattan distance to improve
prediction accuracy for lung cancer diagnosis. The research was conducted using a publicly available
lung cancer dataset consisting of 309 patient records with 14 diagnostic attributes. Comparative experiments
were carried out between the classical K-Medoids and the quantum-enhanced K-Medoids, with
performance evaluated based on clustering accuracy, precision, recall, and F1-score. The results show
that the quantum-based method has the same accuracy as the classical method, namely 88%. This
suggests that quantum-based clustering can match the accuracy of classical methods after adequate
training, although consistency and parameter stability remain areas for further refinement. Further
research is recommended to test the model on larger datasets and to explore real-world deployment in
clinical decision support systems.
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References
[1] Y.-M. Li, H.-L. Liu, S.-J. Pan, S.-J. Qin, F. Gao, D.-X. Sun, and Q.-Y. Wen, “Quantum k -medoids algorithm using parallel
amplitude estimation,” Physical Review A, vol. 107, no. 2, p. 022421, Feb. 2023, https://doi.org/10.1103/PhysRevA.107.022421.
[2] N. Gao, D. Li, A. Mishra, J. Yan, K. Simonov, and G. Chiribella, “Measuring Incompatibility and Clustering Quantum Ob-servables with a Quantum Switch,” Physical Review Letters, vol. 130, no. 17, p. 170201, Apr. 2023, https://doi.org/10.1103/
PhysRevLett.130.170201.
[3] K. Hulliyah and S. Solikhun, “Q-Madaline: Madaline Based On Qubit,” Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi),
vol. 7, no. 5, pp. 1003–1008, Aug. 2023, https://doi.org/10.29207/resti.v7i5.5080.
[4] J. L. Pereira, L. Banchi, and S. Pirandola, “Quantum-Enhanced Cluster Detection in Physical Images,” Physical Review Applied,
vol. 19, no. 5, p. 054031, May 2023, https://doi.org/10.1103/PhysRevApplied.19.054031.
[5] N. Piatkowski, T. Gerlach, R. Hugues, R. Sifa, C. Bauckhage, and F. Barbaresco, “Towards Bundle Adjustment for Satellite
Imaging via Quantum Machine Learning,” in 2022 25th International Conference on Information Fusion (FUSION).
Link¨oping, Sweden: IEEE, Jul. 2022, pp. 1–8, https://doi.org/10.23919/FUSION49751.2022.9841388.
[6] L. Zahrotun, U. Linarti, B. H. T. Suandi As, H. Kurnia, and L. Y. Sabila, “Comparison of K-Medoids Method and Analytical
Hierarchy Clustering on Students’ Data Grouping,” JOIV : International Journal on Informatics Visualization, vol. 7, no. 2, p.
446, May 2023, https://doi.org/10.30630/joiv.7.2.1204.
[7] S. Al-Otaibi, V. Cherappa, T. Thangarajan, R. Shanmugam, P. Ananth, and S. Arulswamy, “Hybrid K-Medoids with Energy-
Efficient Sunflower Optimization Algorithm for Wireless Sensor Networks,” Sustainability, vol. 15, no. 7, p. 5759, Mar. 2023,
https://doi.org/10.3390/su15075759.
[8] F. Faisal, L. A. G. Giopani, M. F. Fitriah, Z. C. D. Dwynne, S. S. H. Helma, and M. Mustakim, “Perbandingan Algoritma
K-Means dan K-Medoids Untuk Pengelompokan Suhu di Provinsi Riau: Comparison of K-Means and K-Medoids Algorithms
for Temperature Grouping in Riau Province,” Indonesian Journal of Informatic Research and Software Engineering (IJIRSE),
vol. 2, no. 2, pp. 128–134, Sep. 2022, https://doi.org/10.57152/ijirse.v2i2.434.
[9] S. Samudi, S.Widodo, and H. Brawijaya, “The K-Medoids Clustering Method for Learning Applications during the COVID-19
Pandemic,” SinkrOn, vol. 5, no. 1, p. 116, Oct. 2020, https://doi.org/10.33395/sinkron.v5i1.10649.
[10] Z.Wu, L. Jin, J. Zhao, L. Jing, and L. Chen, “Research on Segmenting E-Commerce Customer through an Improved K-Medoids
Clustering Algorithm,” Computational Intelligence and Neuroscience, vol. 2022, pp. 1–10, Jun. 2022, https://doi.org/10.1155/
2022/9930613.
[11] Mustakim, M. Z. Fauzi, Mustafa, A. Abdullah, and Rohayati, “Clustering of Public Opinion on Natural Disasters in Indonesia
Using DBSCAN and K-Medoids Algorithms,” Journal of Physics: Conference Series, vol. 1783, no. 1, p. 012016, Feb. 2021,
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