Hubungan Kejadian Gastritis Dengan Riwayat Penggunaan Obat Anti Inflamasi Non Steroid (OAINS) Pada Pasien Yang Melakukan Pemeriksaan Endoskopi

  • Kintan Nandini Nirmala Putri Universitas Bumigora
  • Fitry Apriliany Universitas Bumigora
  • Muh. Wisda Praja Universitas Bumigora

Abstract

Gastritis is defined as inflammation of the gastric mucosa, and one of its causes is the use of medications, specifically Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). The purpose of this research is to examine the relationship between gastritis incidence and the history of NSAID use. The research method employed is an analytical observational study using a Retrospective Cohort design, involving data collection from patients. Data were obtained through interviews with patients and their families, as well as the review of patient medical records during the period of February - May 2023. The statistical test used in this study is the Pearson correlation test. The study mainly included patients aged 36-55 years (46.43%), with 49 respondents being female (58.33%). The results obtained indicate that there is no significant relationship between gastritis incidence and history of NSAID use, with a p-value > 0.05 and an r-value < 1, indicating a weak level of relationship. The conclusion drawn from this research is that the relationship between gastritis incidence and history of NSAID use is weak.

References

Broto, H. D. F. C. (2017). Stres pada mahasiswa penulis skripsi (studi kasus pada salah satu mahasiswa Program Studi Bimbingan dan Konseling Universitas Sanata Dharma). In Universitas Sanata Dharma, Yogyakarta.
Choiro. Miftachul., K. (2014). The Relationship Between Stres Level and Gastritis Symptoms Case of grade IV Students in Thesis Progress of Hang Tuah Health Academy Surabaya. Jurnal STIKES Hang Tuah Surabaya.
Davis, R. A. A. D. D. (2014). The special case of diclofenac. Enliven Arch.
Dipiro, J. . (2019). Pharmacotherapy Handbook. The Mc. Graw Hill Company.
Dwiprahasto, I. (2002). Epidemiologi dan Masalah Penggunaan Analgesik Antiinflamasi Non Steroid. In Penggunaan Analgesik dan Antiinflamasi Secara Rasional.
Hakim, L. N. (2020). Urgensi Revisi Undang-Undang tentang Kesejahteraan Lanjut Usia. Aspirasi: Jurnal Masalah-Masalah Sosial, 11(1), 43–55. https://doi.org/10.46807/aspirasi.v11i1.1589
Istiqomah, Putri, D. E. E., Kurniawan, N., & Santoso, N. E. (2022). Profil Penggunaan Analgetik Pada Penderita Sakit Gigi Di Klinik Dido Dental Care Banyuwangi. Jurnal Farmasi Dan Manajemen Kefarmasian, 1(2), 60–65.
Juwariyah, T., & Priyanto, A. (2018). Hubungan Tingkat Pengetahuan dengan Perilaku Pencegahan Kekambuhan Luka Diabetik. Jurnal Ners Dan Kebidanan (Journal of Ners and Midwifery), 5(3), 233–240. https://doi.org/10.26699/jnk.v5i3.art.p233-240
Katzung, B. G. (2011). Farmakologi Dasar dan Klinik Edisi VIII. Bagian Farmakologi Fakultas Kedokteran Universitas Airlangga.
Kresnadi R, D., & Mulyo, K. (2016). Perbandingan Pengaruh Pemberian Analgetik Cox-2Dengan Asam Mefenamat Terhadap Rasa Nyeri PascaOdontektomi (Impaksi Kelas 1, Molar 3 Rahang Bawah). Jurnal Kedokteran Diponegoro, 5(1), 58–64.
Lestari, P. &. (2008). Endoskopi Gastrointestinal. Salemba Medika.
Miftahussurur, M. (2021). Buku Ajar Aspek Klinis Gastritis. Airlangga University Press.
Rahayu, P. (2016). Buku Ajar Keperawatan Maternitas. Salemba Medika.
Singgih, M. F., Achmad, H., Sukmana, B. I., Carmelita, A. B., Putra, A. P., Ramadhany, S., & Putri, A. P. (2020). A Review of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Medications in Dentistry: Uses and Side Effects. Systematic Reviews in Pharmacy, 11(5), 293–298.
Sinha, M., Gautam, L., Shukla, P. K., Kaur, P., Sharma, S., & Singh, T. P. (2013). Current Perspectives in NSAID-Induced Gastropathy. 2013.
Srikandi Ardiansyah, E. E. P., Herda Ariyani, & Hendera. (2021). Studi Literatur Efek Penggunaan Non-Steroidal Anti Inflammatory Drugs (Nsaid) Pada Sistem Gastrointestinal (Literature Study Of The Non-Steroidal Anti Inflammatory Drugs (Nsaids) On The Gastrointestinal System). Journal of Current Pharmaceutical Sciences, 5(2598–2095), 418–428. https://journal.umbjm.ac.id/index.php/jcps/article/view/791
Sukarmin. (2013). Keperawatan Pada Sistem Pencernaan. Pustaka Pelajar.
Suwindiri, Yulius Tiranda, W. A. C. N. (2021). Faktor Penyebab Kejadian Gastritis Di Indonesia : Literature Review Mahasiswa IKesT Muhammadiyah Palembang , Sumatera Selatan , Indonesia IKesT Muhammadiyah Palembang , Sumatera Selatan , Indonesia. Jurnal Keperawatan Merdeka (JKM), 1(November), 209–223.
Usmadi, U. (2020). Pengujian Persyaratan Analisis (Uji Homogenitas Dan Uji Normalitas). Inovasi Pendidikan, 7(1), 50–62. https://doi.org/10.31869/ip.v7i1.2281
Valentine, P. F., & Tina, R. (2013). Pengaruh Polimorfisme CYP2C9*2 dan CYP2C9*3 terhadap Resiko Pendarahan Saluran Gastrointestinal Terapi NSAID. Farmaka Suplemen, 14(1), 1–15.
WHO. (2016). World Health Statistics.
Yanti. (2010). Buku Ajar Kebidanan. Pustaka Rihama.
Published
2024-04-30