TY - JOUR AU - Nella Sudianjaya AU - Chastine Fatichah PY - 2024/11/15 Y2 - 2025/04/03 TI - Segmentation and Classification of Breast Cancer Histopathological Image Utilizing U-Net and Transfer Learning ResNet50 JF - MATRIK : Jurnal Manajemen, Teknik Informatika dan Rekayasa Komputer JA - matrik VL - 24 IS - 1 SE - Articles DO - https://doi.org/10.30812/matrik.v24i1.4186 UR - https://journal.universitasbumigora.ac.id/index.php/matrik/article/view/4186 AB - Breast cancer is the most common type of cancer among various types of cancer. Approximately 1 in 8 women in the United States die from breast cancer. Early screening and accurate diagnosis are essential for prevention and accelerated treatment intervention. Several artificial intelligence methods have emerged to develop effective segmentation, detection, and classification to determine cancer types. Although there has been progress in automated algorithms for breast cancer histopathology image analysis, many of these approaches still face several challenges. This study aims to address the challenges in breast cancer image analysis. This research method uses the development of the U-Net architecture combined with Transfer Learning using ResNet50. The encoder path aims to improve the model’s sensitivity in the segmentation and classification of cancer areas by utilizing deep hierarchical features extracted by ResNet50. In addition, data augmentation techniques are used to create a diverse and comprehensive training dataset, which improves the model’s ability to distinguish between different tissue types and cancer areas. The results of this study are U-Net and ResNet50, which show an average IoU of 0.482 and a Dice coefficient of 0.916. This study concludes that integrating UNet with Transfer Learning ResNet50 improves the segmentation and classification accuracy in breast cancer histopathology images and overcomes the problem of high computational requirements. This approach shows significant potential for improvement in early breast cancer detection and diagnosis. ER -